In toxicology, Björklund Pharma introduces DAE-DTH and BDTH2, two powerful thiol-based antioxidants and metal chelators engineered to effectively penetrate cell membranes. These compounds are designed to mitigate the toxicity of hydroxyl free radicals, thereby aiding in the restoration of normal redox balance.
Product Candidates
Diaminoethyl-dithiolhexane
Diaminoethyl-dithiolhexane (DAE-DTH), also known as 1,4-bis(2-aminoethyl)-2,5-dithiolhexane, is a chelating agent developed by Björklund Pharma with a specific affinity for mercury ions (Hg2+). Read More
BDTH2
BDTH2 (N,N′-bis-(2-mercaptoethyl) isophthalamide, NBMI, emeramide) is a thiol-redox antioxidant and metal chelator. The drug penetrates cell membranes, crosses the blood-brain barrier, and has antioxidant properties for scavenging and reducing the toxicity levels of hydroxyl free radicals, which are dangerous for the cells’ normal redox status. Read More