In dermatology, Björklund Pharma presents innovative skincare solutions: InBio Paeonol + Zinc for inflammatory skin conditions, and InBio Vital Skin, which combines phenylthiol hydroxyether with essential nutrients for antioxidant protection, collagen stimulation, and improved skin texture. Phenylthiol hydroxyether contributes antimicrobial and barrier-enhancing properties, while thymosin beta 4 demonstrates promise in reducing healing time.
Product Candidates
InBio Paeonol + Zinc
InBio Paeonol + Zinc is a dermatological ointment formulated with natural ingredients renowned for their therapeutic efficacy in managing inflammatory skin conditions. The product includes paeonol extract, zinc oxide, aloe vera gel, shea butter, and olive oil. Paeonol, derived from Paeonia suffruticosa, possesses potent anti-inflammatory and antioxidant properties that help soothe and reinforce the skin barrier, making it particularly beneficial for eczema and dermatitis.
Zinc oxide is known for its antimicrobial and wound-healing effects, supporting skin regeneration and reducing redness and discomfort associated with inflammatory conditions. Aloe vera gel hydrates the skin, accelerates wound healing, and alleviates itching and irritation. Shea butter nourishes and fortifies the skin’s natural barrier, ideal for dry and sensitive skin types. Olive oil shields and replenishes the skin, enhancing elasticity and supporting repair processes.
The synergistic action of these natural ingredients in InBio Paeonol + Zinc offers a holistic approach to calming and fortifying inflamed skin. This formulation is suitable for individuals affected by eczema, dermatitis, or pruritus, providing gentle yet effective relief for sensitive and irritated skin. For topical application, apply a thin layer to affected areas and gently massage until absorbed, avoiding contact with eyes or mucous membranes. If skin irritation occurs, discontinue use and consult with a healthcare professional.
InBio Vital Skin: Advanced Anti-Aging Formula
InBio Vital Skin is an advanced anti-aging formula that combines phenylthiol hydroxyether (C6H5-SH | C6H5-O-C6H5-OH | -OH) with essential nutrients, including vitamin E, hyaluronic acid, peptides, resveratrol, coenzyme Q10, niacinamide, and green tea extract. This synergistic blend provides antioxidant protection, boosts collagen production, improves skin texture, and enhances hydration.
InBio Vital Skin is a lightweight moisturizing gel or lotion designed to improve skin quality and resilience.
Phenylthiol Hydroxyether: Dermatological Potential
Phenylthiol hydroxyether, characterized by a phenyl ring linked to a thiol (-SH) group, hydroxyl (-OH) groups, and ether (-O-) functionalities, demonstrates dermatological applications. This compound exhibits antimicrobial activity beneficial for acne management, enhances skin barrier integrity, and functions as an efficient vehicle for topical drug delivery in skincare formulations.
The multifaceted properties of phenylthiol hydroxyether underscore its potential as a versatile component in dermatological therapeutics.
Spongiderm
Spongiderm, a product candidate from Björklund Pharma, utilizes compounds from the freshwater lake sponge Spongilla lacustris to treat moderate to severe acne, mild to moderate psoriasis, and moderate to severe rosacea. The sponge’s silica spicules exfoliate the skin, stimulate collagen production, and unclog pores while enhancing the delivery of antimicrobial and anti-inflammatory compounds like spongin and bioactive silica.
Research shows the compounds in Spongiderm effectively reduce inflammation and bacteria, targeting acne-causing Cutibacterium acnes. With a once-weekly application, Spongiderm offers a potentially faster and more effective treatment for inflammatory skin conditions than existing products.
Thymosin Beta 4 in Dermal Healing
Unlike many pharmacological treatments for various pathologies, much is known about the mechanisms of action of thymosin beta 4 (Tβ4). The active site(s), receptor, signaling pathways, and biological activities are known. The safety profile is excellent, and no preclinical toxicology has been found (1).
Efficacy trends have been observed in phase 2 clinical trials, which reduced the healing time by almost half. Also, a near-optimal dose (0.02–0.03%, w/w) has been identified in dosing studies for dermal healing. Finally, no adverse reactions have been observed with topical or injected Tβ4 in humans, and no autoantibodies have been detected. Tβ4 is a naturally occurring molecule that relatively cheaply can be synthesized. The cost is important given that other treatments are not widely used due to the high cost and limited efficacy (1).
Reference
- Kleinman HK, Sosne G. Thymosin β4 promotes dermal healing. Vitam Horm 2016;102:251-75. doi: 10.1016/bs.vh.2016.04.005.
Dermatology
In dermatology, Björklund Pharma offers a range of innovative skincare solutions designed to address various skin concerns, including inflammatory conditions, acne, anti-aging, and advanced wound healing. Our products combine the power of natural ingredients with advanced therapeutic compounds to promote healthier, more resilient skin.
Product Candidates
InBio Paeonol + Zinc
InBio Paeonol + Zinc is a dermatological ointment formulated with natural ingredients known for their therapeutic efficacy in managing inflammatory skin conditions. This product combines paeonol extract, zinc oxide, aloe vera gel, shea butter, and olive oil to soothe, protect, and reinforce the skin barrier. It is particularly beneficial for individuals with eczema, dermatitis, or pruritus, providing gentle yet effective relief for sensitive and irritated skin. [Read More]
InBio Vital Skin: Advanced Anti-Aging Formula
InBio Vital Skin is an advanced anti-aging formula that combines phenylthiol hydroxyether with essential nutrients, including vitamin E, hyaluronic acid, peptides, resveratrol, coenzyme Q10, niacinamide, and green tea extract. This synergistic blend provides antioxidant protection, boosts collagen production, improves skin texture, and enhances hydration, making it ideal for those seeking to improve skin quality and resilience. [Read More]
Spongiderm
Spongiderm utilizes compounds from the freshwater sponge Spongilla lacustris to treat moderate to severe acne, mild to moderate psoriasis, and moderate to severe rosacea. The sponge’s silica spicules exfoliate the skin, stimulate collagen production, and unclog pores, while its bioactive compounds reduce inflammation and bacteria. Spongiderm offers a natural, effective treatment for inflammatory skin conditions with a once-weekly application. [Read More]
Thymosin Beta 4 in Dermal Healing
Thymosin Beta 4 is an advanced therapeutic candidate demonstrating promise in reducing healing time and enhancing tissue regeneration. Its application in dermal healing is supported by clinical research, making it a potential option for those requiring advanced wound care. [Read More]
HydraBoost (New Addition)
HydraBoost is an intensive hydration serum formulated to combat dry and dehydrated skin. It features a blend of hyaluronic acid, ceramides, and glycerin, which work together to deeply moisturize and strengthen the skin barrier. This serum is ideal for individuals with dry or sensitive skin, providing long-lasting hydration and protection. [Read More]
RadianceCorrect (New Addition)
RadianceCorrect is a skin brightening and tone-correcting serum designed to address hyperpigmentation and uneven skin tone. It contains vitamin C, niacinamide, and licorice root extract, which work synergistically to reduce dark spots, enhance skin radiance, and improve overall complexion. [Read More]
InBio ImmunoSkin
InBio ImmunoSkin is a nutritional supplement that enhances immune defenses and supports skin health. It combines Astaxanthin, a potent antioxidant, with highly absorbable Zinc Bis-Glycinate. This blend is ideal for boosting immunity and maintaining skin vitality, especially during stress or environmental exposure. Read More
InBio ImmunoSkin
InBio ImmunoSkin is a nutritional supplement formulated to boost immune defenses and support skin health. This supplement combines Astaxanthin, a powerful antioxidant, with Zinc Bis-Glycinate, a highly absorbable form of zinc. The combination of these ingredients is particularly beneficial for individuals looking to enhance their immune function while maintaining healthy skin, making it an ideal daily regimen during periods of high stress or environmental exposure.
Each capsule of InBio ImmunoSkin contains 4 mg of Astaxanthin, known for its ability to protect cells from oxidative damage. Astaxanthin supports the immune system by enhancing the body’s natural defenses and reducing inflammation. It also promotes skin health by improving elasticity, reducing fine lines, and protecting against UV-induced damage.
In addition to Astaxanthin, each capsule provides 15 mg of elemental zinc in the form of Zinc Bis-Glycinate. This chelated form of zinc offers superior absorption and is essential for immune cell function, wound healing, and inflammation regulation. Zinc also aids in collagen synthesis, maintains skin integrity, and can reduce the severity of acne and other skin conditions.
InBio ImmunoSkin is intended for individuals who wish to strengthen their immune system and maintain healthy skin. It is especially suitable for those facing high stress, increased environmental exposure, or needing additional support for immune and skin health. The recommended dosage is one capsule daily, taken with meals to enhance absorption. Consistent daily use is advised to achieve the best results.
The product is generally well-tolerated, though it should not be used by individuals with known sensitivities to any of its components. Pregnant and lactating women should consult a healthcare provider before use. Those with a history of zinc-related sensitivities or those already taking high doses of zinc should seek medical advice before starting this supplement.
While mild gastrointestinal discomfort may occur with zinc supplementation, Astaxanthin is well-tolerated. Any adverse reactions should be reported to a healthcare professional, and use should be discontinued if severe reactions occur. Zinc may interact with certain medications, such as antibiotics and antacids, so it is recommended to take InBio ImmunoSkin at a different time of day from these medications to avoid potential interactions.
InBio ImmunoSkin should be stored in a cool, dry place, away from direct sunlight and moisture. The product should be kept out of reach of children and has a shelf life of 24 months from the date of manufacture. It is available in bottles containing 60 capsules, providing a two-month supply with the recommended daily dosage.
InBio ImmunoSkin offers a comprehensive solution for those seeking to enhance immune function and maintain healthy skin. By combining Astaxanthin and Zinc Bis-Glycinate in a single supplement, it addresses two key areas of health, making it an ideal choice for daily use, particularly during times of increased stress or environmental challenges.
